Sentence examples for basal levels of oxidative from inspiring English sources

The basal levels of oxidative DNA damage, and effects of the interventions have been rather variable, possibly reflecting differences in the populations, regimens, and the type of assays.

For example, moderate exercise training alters oxidative homeostasis by reducing basal levels of oxidative damage [60], and by increasing resistance to oxidative stress, mediated largely through increased endogenous antioxidant defenses [60,62].

In order to determine basal levels of oxidative stress in fibroblasts from Parkin mutants, we applied an OxyBlot.

Resting T cells, including both naïve and memory T cells, derive most of their adenosine triphosphate (ATP) from basal levels of oxidative phosphorylation (OXPHOS) [1], [2], [3].

The elevation we observed in MDA in the skeletal muscle of G93A mice, which exhibit increased basal levels of oxidative stress [32], is in accordance with the heightened oxidative damage observed in the study by Gursoy et al (2000), which used another animal model with higher basal levels of stress [39].

In the present study, we show that frataxin deficiency in murine liver is associated with increased basal levels of oxidative DNA base damage.

Our analysis revealed an increase of the basal level of oxidative damage in the nuclear DNA of G3 mTerc -/- mice compared to mTerc + mice, but heterozygous deletion of Sod2 had no influence.

Of direct relevance in this connection is the recent identification of elevated mitochondrial bioenergetics (higher basal level of oxidative phosphorolyation, greater axonal mitochondrial density) and high complexity of axonal arborization as major contributors to the hightened vulnerability of nigral dopamine neurons to toxic agents.

The increased basal level of oxidative stress in cancer cells is attributable to the activation of the Akt kinase signaling cascade, which increases cellular ROS and impairs of some enzymatic ROS detoxifying mechanisms, as well an increased generation of ROS from NADPH oxidase (Nox) [ 1, 3].

Both these drugs when given alone to non-stressed animals did not alter basal levels of antioxidant defense components and oxidative stress markers significantly.

We have recently observed that a multi-talented protein, SNEV, extends the replicative life span of endothelial cells upon overexpression, reduces basal levels of DNA damage and suppresses oxidative stress induced apoptosis in these cells [ 39].