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Second, the TNF-α promoter exhibits high basal levels of gene expression (Fig. 3C).
The rats tested in the open field test were sacrificed by rapid decapitation on PN48 (7 days after the open field test so that we were measuring basal levels of gene expression, not the effect of the open field test).
However, it appears that repeated bouts of exercise lead to new basal levels of gene expression in resting muscle.
Proximal promoter regions (~500 bp upstream and 100 bp downstream of the TSS) typically contain the features necessary for basal levels of gene expression.
There was no difference in the basal levels of gene expression for MMP-3, -9 or -13 between untreated normal and degenerate NP cells (data not shown).
The association was seen to be reproducible between biological replicate experiments and also be present in the basal levels of gene expression observed in this cell type.
Similar(48)
The mprAB operon has a basal level of gene expression [18], [19] irrespective of the operation of the positive feedback loop.
It has been also documented that TRB3 is involved in the control of the basal level of gene expression under control/unstarved conditions [24].
As a result, the model stays closer to reality where a basal level of gene activity is present and genes are seldom seen to exhibit purely binary state behavior.
Increased binding affinity for S increases the basal level of gene expression.
The mprAB operon has a basal level of gene expression independent of the operation of the positive feedback loop.
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