Your English writing platform
Discover LudwigSuggestions(5)
Exact(25)
Interestingly, frataxin-defective cells had increased basal level of phosphorylated p53 but a less efficient activation of p53 on hypoxia.
Similarly to FRDA cells, frataxin knockdown HeLa and U118 cells had increased basal level of phosphorylated p53 compared with control cells.
However, while we found reduced insulin-induced phosphorylation of AKT, the basal level of phosphorylated AKT and of one of its downstream targets ribosomal protein S6 was similar between tumors of HCD-pre-tumor-onset and SD Kras G12D mice.
Although increased phosphorylation of AKT did not occur with any of the chemotherapeutic agents in OVCAR-3 cells, which exhibited a high basal level of phosphorylated AKT, NO-Cbl reduced the high basal AKT phosphorylation levels.
Confirming previous results, PI3Kγ−/− hearts exhibit a much higher basal level of phosphorylated PLB (Figure 4E).
In parallel, analysis of Rb−/− cells revealed a basal level of phosphorylated IkB that was slightly increased between 1 and 4 hpi.
Similar(35)
The SASP of non-classical monocytes is likely induced by high basal levels of phosphorylated NF-κB (p65) (Fig. 6), which is a transcription factor for pro-inflammatory cytokines, and incidentally, also miR-146a.
ER-Src cells treated with the vehicle EtOH, but not TAM-treated MCF10A cells carrying an empty vector (PBabe; Supplementary Fig. 1), showed basal levels of phosphorylated ER-Src (ER-pSrc), indicating that ER-Src displays some degree of leakiness.
Depressed cytosolic Ca2+ removal was not, however, associated with changes in basal levels of phosphorylated PLB, nor levels of SERCA, NCX or PLB proteins.
In contrast, the monovalent Fab fragment of Anti-MUC1* suppressed basal levels of phosphorylated ERK1/2 (Fig. 3F).
Accordingly, we examined the influence of culling on the effects of neonatal DEX treatment on the basal levels of phosphorylated CaMKIIα at threonine-286 and PP1 protein expression.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com