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This suggests a tetraploid-specific basal level of activation of the Slt2p-mediated cell wall integrity (CWI) pathway.
The currently favored approach is over-expression of σ to facilitate detection of σ-dependent promoters, which assumes a reasonable basal level of activation of the bEBPs.
Although the NRF asserts a basal level of activation through enhancements in ADP release, full activation is achieved through an NRF RS2 connection.
The first is the growth-rate trend of the SLT2 deletion series, which revealed a tetraploid-specific basal level of activation of the SLT2 cell wall integrity pathway.
Two reasonable choices for a characteristic concentration would be the basal level of activation of the gene under no input, or the maximal or steady state level of activation of the gene under its own input.
Noteworthy, while STATc is massively cytosolic in early developing cells, we could detect some staining in the nucleus of growing cells suggesting a basal level of activation of the transcription factor in vegetative conditions.
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This constitutive phosphorylation could be due to the relatively high basal levels of activation of this cell line [26].
We determined that without serum complement C1q or C6, the basal levels of activation or nuclear accumulation of ERK and WOX1 were reduced significantly, whereas constitutive activation of JNK1 occurred.
These results suggest that Tbdn is involved in the regulation of basal levels of activation of SFK.
This indicates that when Tbdn levels are reduced in these cells, the transcellular pathway is still responsive to Albumin while the basal levels of activation of SFK are higher than normal.
Interestingly, the magnitude of glucose-induced activation of PP2A in a ppe1Δ strain was higher than in the WT strain, without altering the basal level of activity.
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