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Likewise, the incidence of tumor and their multiplicity in response to N-nitrosomethylbenzylamine in the fore-stomach was decreased in transgenic mice overexpressing ODC antizyme in the basal layer of cell of the fore-stomach epithelium [ 58].
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The interfollicular epidermis is a multi-layered epithelium in which the basal layer of cells is attached to an underlying extracellular matrix (ECM), known as the basement membrane, and the suprabasal layers comprise cells that undergo terminal differentiation, culminating in formation of the barrier that protects the body from water loss and penetration by micro-organisms.
However, p63 stained the epithelial component in one papillary carcinoma, a basal layer of cells in 1 biphasic invasive carcinoma, and the cytoplasm in 1 case.
As expected the p63 signal strongly stains the first basal layer of cells and its intensity gradually decreases (Fig. 8A).
Following this treatment, purified neurons were isolated by mechanically dislodging the neurons from the basal layer of cells and replated on PLO/Matrigel or Geltrex in the same media without cytosine arabinoside, fluorodexoyuridine, or uridine.
In normal epidermis, integrin β1 is localised to lateral and basal membranes in the basal layer of cells.
In contrast, LacZ expression was observed in the proximal region, and expression was contained with the basal layer of cells.
Basal-like breast cancers are characterized by expression of genes that pertain to the basal layer of cells in normal mammary glands, such as CK5/6 and CK14.
One, known as basal-like tumors, expresses high levels of myoepithelial cytokeratins found in the outer basal layer of cells in a normal breast duct.
In normal skin, integrin α2 and α3 were expressed in the basal layer of cells and localised to the lateral membranes.
Staining with P5D2 revealed that in normal vulval epidermis integrin β1 is expressed in the basal layer of cells in contact with the basement membrane and a small number of cells in the suprabasal layer.
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