Sentence examples for basal expression of cell from inspiring English sources

In primary ALL cells, global gene expression profiling revealed JQ1-induced downregulation of multiple pro-survival pathways and a therapeutic response dependent on the basal expression of cell cycle regulators c-Myc and its target p21.

Increased basal expression of the cell adhesion receptor, CD44, was a unique trait exhibited by naïve, CD62L-positive Rasgrp1 Anaef T cells.

Pat-5 and Pat-6 cells showed inhibition of marker expression in spheroidal cultures, but they exhibited significant basal expression of stem cell-related factors already in adherent-growing cultures.

In both assays, basal expression of cDNAs from cells transiently transfected with empty vector was statistical set as fold change of 1 (no change).

The basal expression of cMET in the cell lines with elevated Wnt activity is low, but stimulated when the PI3K/mTOR pathway is blocked; blocking this pathway also affects the EGFR and HER2 expression.

Based upon experimental data demonstrating low basal expression of versican in 66c14 cells, a versican G3 construct was stably expressed in 66c14 cells using established techniques [22],[22].

When the degranulation activity of NK cells was investigated by measurement of CD107a expression, the basal expression of CD107a on NK cells from healthy donors was less than 1%.

We observed highest basal expression of BST-2 in cells of the monocytic lineage (CD14+ primary monocytes and THP-1 cells, Fig. 1A and C), while lower basal expression of BST-2 was observed in primary T cells (Fig. 1B), with the lowest expression of BST-2 on Jurkat cells (Fig. 1D).

The RT-PCR results confirmed earlier observation from our cDNA microarray analysis that unirradiated HCT116Clone2_XRR cells had lower basal expression of XRRA1 than unirradiated HCT116Clone10 cells (Fig. 4, Table 5).

Basal expression of CXCR4 varied between CRC cell lines with HT-29 cells having the highest expression (Table  1).

Basal expression of FGFR4 in these resistant cell lines was similar to the parental cell line (Supplementary Figure S3).