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Finally, we labeled proliferating basal epithelial cells in vivo to show differing cell-cycle profiles and proliferation kinetics.
Because the esophageal epithelium lacks a defined stem cell niche, it is unclear whether all basal epithelial cells in the adult esophagus are functionally equivalent.
K14 was localized predominantly to basal epithelial cells in the limbus and suprabasal epithelial cells in the central cornea.
Recently, high expression of Tacstd2 has been identified in basal epithelial cells of the proximal prostate, but not in basal epithelial cells in the more distal prostate [38].
We previously demonstrated that there is an expansion of prostate basal epithelial cells in a PB-Cre Ptenfl/fl mouse model, in which PB-Cre Ptenfl/flally deleted in both the prostate basal and lumouse epithelial cells [35], [36].
Basal epithelial cells in normal tissue adjacent to each tumour served as an internal positive control.
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The cumulative distribution of the scores in the basal and luminal epithelial cells is shown in Fig. 1B, where it is clear that the median FAAH-IR is higher in the basal epithelial cells than in the luminal cells.
After flutamide exposure we showed a positive staining for ARs (though of various intensity) in the principal and basal epithelial cells and in the stroma layer throughout the epididymis.
The presence of BSA in cell culture media reduced the cellular uptake of BSA-uncoated GONs on human embryonic kidney cells 293 (HEK 293) and human adenocarcinoma alveolar basal epithelial cells (A549) in the media without FBS addition.
It has been proposed that the focal limbal irradiation of basal epithelial cells results in the alteration of these cells and a breakdown of the limbal barrier [ 30].
Indeed, activation of β-catenin within the basal epithelial cells results in premature differentiation of the luminal epithelium during pregnancy and persistent proliferation resulting in tumors.
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