Sentence examples for basal definition from inspiring English sources

Basal definition of M30 corroborates with earlier works [22].

Of note, in GEICAM/2006-03, elincludedy included the 'core basal' definition (Nielsen et al, 2004), a more restrictive TNBC definition (that is, TNBC status plus immunostain positive for either cytokeratin 5/6 or EGFR).

If the alternative 'core basal' definition is used to define the basal phenotype (triple-negative cases with any expression of CK5/6 and/or epidermal growth factor receptor (EGFR) [ 24]), calpain-2 expression remains statistically associated with survival for patients with core basal tumours (P = 0.050).

In a subsequent study, Cheang and colleagues observed superior prognostic value of the basal-like immuno-histochemical definition (core basal) using these four biomarkers (plus progesterone receptor negativity) than when using the standard estrogen receptor-negative/progesterone receptor-negative/HER2-negative definition [ 6].

By definition, basal cell carcinoma is cancer of the basal cells, which the Mayo Clinic describes as "a type of cell within the skin that produces new skin cells as old ones die off".

Hence, the basal cytokeratin-based definition that has been widely used in the literature (Rakha et al, 2006, 2008) and in this study is probably more relevant in the authors' opinion.

Moreover, the definition of basal phenotype in breast tumours is conflicting; for example, not all tumours classified as basal-like by microaray analysis express basal CKs [ 2].

A pragmatic definition of basal phenotype, whereby expression of cytokeratin (CK -5/6 and/or CK -5/6bove 10% wand/orined as basal phenotype, irrespective of ER, PgR or HER2 receptor stabove was used for this study [ 20].

The definition of basal cancer is derived from genetics, Sledge said, while triple negative cancer is classified as such depending on whether a tumor's growth is fueled by the hormones estrogen, progesterone and the gene HER2.

By definition, the basal cell signature should exclude genes expressed selectively or more abundantly in ciliated and secretory cell types.

32 However, methodological issues with this study make it difficult to interpret, including their reliance on basal hormone measurements, the definition of normal ranges from a small cohort of control subjects, and the nonstandard assessment of posterior pituitary function.