Sentence examples for basal activity of a from inspiring English sources
Dual-channel FACS analysis revealed that neither active nor inactive ER-ChaC1CtoS-mCherry-KDEL measurably affected the basal activity of a stably integrated mammalian UPR reporter, CHOP GFP (Novoa et al., 2001) (reflected in the absence of a shift to the right in the mCherry positive population of cells, Figure 6A, left column).
Certain TF's may contribute to the basal activity of a promoter being responsible for tissue specificity, whereas others modulate the level of expression.
This value corresponds to a moderately strong transcription activity; note that transcription activity of very strong rRNA promoters is ~60 min-1, while basal activity of a very weak uninduced λPRM promoter is ~1/7 min-1[ 17].
In contrast, basal activity of class-A GPCRs may originate from spontaneous deprotonation at D2.50.
When integrated in cells, this sensor turned out to be mostly cytoplasmic, suggesting that a high basal activity of the MAPK resulted in a constitutive phosphorylation of the sensor.
Sphingomyelinase treatment resulted in a directly analogous increase in basal activity of both AC8 forms and a loss of stimulation by CCE (Fig. 5 A, inset).
An activity level of 0 represents the basal activity of the node, while an activity level of 1 or -1 describes a node which is maximally activated or maximally inhibited, respectively.
As we show the presence of a significant basal activity of CFTR in Calu-3 cells, it can be concluded that CFTR function as a chloride channel is not linked to DRM relocalization of cPLA2α and ANXA1.
In the SCC-9 cells, the Ki16425 completely inhibited the LPA-induced migration, decreasing it to a level below the controls, suggesting a basal activity of LPAR3 in the SCC-9 cells.
This does not, however, discard the possibility that the alternative pathway(s) require a basal activity of PKA, even if they do not depend on its activation by cAMP.
Secondly, the low to moderate basal activity of the dual reporter offers a potential capability to monitor both an increase or decrease in gene expression (unpublished data).
