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In contrast, PKM2 has low basal activity and is activated by an effector molecule fructose 1,6-bisphosphate (FBP).
The h700 bp has a higher basal activity and is activated 10-fold by both enhancers.
No activation above basal activity occurred when pMSCVGRQCIMFI was transfected under different conditions.
It induces death when strongly activated, but its basal activity is necessary to avoid growth arrest.
CaMKKβ is activated by Ca2+ and calmodulin, but also has a substantial basal activity [ 13].
Serotonin 5-HT2C RNAeditingNaltersing altereceptortor basal activity: implications for serotonergic signal transduction.
Many GPCRs show basal activity to various extents even in the absence of any stimulating ligands.
Peak activity was 77.3 ± 19.5 index value (approximately 7.7 SD from basal activity) on HT.
(c) Quantification of TORC2 basal activity, monitored by Ypk1 T662 phosphorylation, in WT and mss4-103 cells at the permissive (30 °C) and non-permissive (37 °C) temperatures.
Session 1: Subjects received a placebo drink to determine the presence of differences in the basal activity of the HPA-axis as a function of family history.
Kudlow, B.A., Zhang, L. & Han, M. Systematic analysis of tissue-restricted miRISCs reveals a broad role for microRNAs in suppressing basal activity of the C. elegans pathogen response.
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