Sentence examples for barrier with subsequent from inspiring English sources

PN results in a major breakdown of the gut mucosal defense barrier with subsequent bacterial/endotoxin translocation, leading to sepsis and infections locally and at distant sites.

Moreover, with the rapidly expanding use of medical devices (e.g., indwelling catheters) and increases in the number of patients receiving antibiotic and immunosuppressive therapies, there is an increased risk of fungal penetration through mucosal barriers with subsequent entry into the blood stream, which often leads to multi-organ infections.

Blood brain barrier damage with subsequent passive transferrin-bound iron leakage into the lesions may increase the iron content.

Importantly, if the epithelium cell death is not strictly regulated, it might result in a barrier defect with subsequent microbial invasion and inflammation.

As a consequence of accelerated loss of gastrointestinal epithelial cells, the intestinal wall losses its barrier function with subsequent leakage of endotoxin and bacteria into the systemic circulation [ 56, 57].

DSS is directly toxic to gut epithelial cells of the basal crypts and affects the integrity of the mucosal barrier with the subsequent infiltration of immune (especially innate) cells (12).

Nevertheless, hyperglycemia damages the endothelial cells and pericytes and increases vascular permeability with rupture of the blood-retinal barrier with the subsequent appearance of the retinal hypoxia processes, which, in turn, induces vascular endothelial growth factor (VEGF) expression, among other proangiogenic effectors [ 14, 15].

For brain metastasis, blood brain barrier (BBB) disruption with subsequent increased vascular permeability and leucocyte migration into the brain is pivotal.

As the adoption of wearable devices spreads, there are cultural and social impacts that represent both barriers and opportunities, with subsequent policy ramifications.

The implementation of strict IPAC practices, including hand hygiene and active surveillance of colonized patients with subsequent barrier precautions, has been credited for the declining rates of MRSA catheter-related bloodstream infections by 50% or more in medical, surgical, cardiac and pediatric ICUs since 2001 [ 15].

SHRSP, an animal model of chronic arterial hypertension, develop a broad spectrum of CSVD histopathology, including early microvascular dysfunction with subsequent blood brain barrier breakdown.