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Therefore, it is a key barrier to develop and employ robust inhibitor-tolerant microorganisms for economic lignocellulosic biofuel production.
If resistance testing is not possible or the patients needs to commence treatment before resistance results are available in case of low CD4 numbers, it may be advisable to initiate treatment with a boosted PI-regimen [40], Taking into account that boosted PIs have a higher barrier to develop resistance, an accumulation of mutations is required to induce PI-related resistance.
These considerations make it likely for a reproductive barrier to develop in this way.
Our approach overcomes a barrier to develop small molecule therapies targeting HER3.
Numerous adult and pediatric studies have shown a high virologic potency, an excellent toxicity profile and a high barrier to develop resistance.
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Usually reagents must be refrigerated in order to work, which presents a huge barrier to developing tests for places that lack steady electricity.
Historically, the barrier to developing for feature phones has been sluggish operating systems that are less integrated with other features of the phone.
Hosted by Time to Change and Mellow, an African-Caribbean mental health organisation, the festival's theme is "belonging" as mental health stigma can be a barrier to developing and maintaining relationships in the community.
Another area of emphasis was to study the extent to which access to IPR by researchers and companies was a barrier to developing new GMO technologies, especially in developing new foods for the poor.
As a medical humanitarian organization providing vaccines and treating diseases around the world, we fear that this provision would create another barrier to developing affordable generic versions of cutting-edge drugs.
A major barrier to developing new treatment protocols is the clinical-trial system, says Blackwell.
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