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The intestinal epithelium is the main barrier restricting the oral delivery of low-permeability drugs.
But the highest wall of all — the information barrier restricting knowledge of the wider world and its ways — is crumbling fast.
This tribo-layer becomes a barrier restricting direct contact of steel with the coating and thus preventing it from further intense wear.
Such host cells formed a barrier restricting bacteria to necrotic areas and prohibited bacterial spread within the tumor.
Secondly, coelenterazine is a substrate for p-glycoproteins that are highly expressed at the blood brain barrier, restricting coelenterazine access to the brain [29].
Under normal conditions, the intestinal epithelium acts as a protective barrier restricting transport of luminal antigens, and only allows small and selective quantities to permeate the mucosa [16] [18].
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In spite of, numerous research efforts, which have been devoted to the isolation of series peptidic and non-peptidic CRFRs agonists, the poor penetration across blood brain barrier restricts, their wide application in the clinical practice.
Recharge of P-SGw to deep groundwater in the proximal-fan region (P-DGw) is obvious, because δ values of P-DGw are similar to those of P-SGw and no barrier restricts P-SGw entering P-DGw.
In general, the language barrier restricts conversation between the tourists and the Tuaregs.
The barrier restricts substances to be absorbed.
It acts as a physical barrier, restricts cellulase access to cellulose and, thereby, reduces the activity of the enzyme through non-productive binding [ 20].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com