Sentence examples for barrier innate from inspiring English sources
Due to the unique condition of being constantly exposed to air that contains pathogens, allergens, and pollutants, the lung has developed a highly specific local microenvironment where the combined actions of the epithelial barrier, innate defense molecules, and responses of both, the epithelium and professional phagocytes, help to maintain biophysical and immune homeostasis.
Endoparasites are confronted with host defenses at multiple levels: physical barriers, innate immunity, and adaptive immune responses need to be overcome in order to successfully establish an infection and proliferate inside a host.
The pathogenesis of IBD is complex and involves susceptibility genes, the epithelial barrier function, innate and adaptive immunity and environmental factors including bacteria [26].
The bacterial surface provides the first barrier against innate immune mechanisms as well as mediating attachment to cells/surfaces to resist clearance.
At the same time, the epidermis acts as first-line barrier in innate immunity and, as such, maintains complex communication with resident dendritic cells and sub-epidermal endothelial cells and fibroblasts.
We hypothesized that prematurity and inflammation, either alone or combined, disturb maturation of the gut barrier, the innate immune defense and vascular function thereby potentially increasing the risk to postnatal intestinal pathologic conditions.
The intestinal epithelium is composed of three functional barriers: a physical barrier, an innate immune barrier and an adaptive immune barrier [ 38].
Alcohol-induced changes in microbial flora of the gut and vaginal compartments as well as changes to the epithelial barrier and innate defenses may alter the efficacy of antiviral approaches.
If a pathogen breaches these barriers, the innate immune system provides an immediate, but non-specific response.
The IS of vertebrates is composed by three layers of defense: (a) the physical barriers; (b) innate IS; and (c) the adaptive IS.
Once an organism breaches the integument or mucous membrane barriers, the innate immune system must recognize this potential threat and orchestrate an appropriate response to surround and eradicate the pathogen.
