Sentence examples for barrier function of the stratum from inspiring English sources

The barrier function of the stratum corneum is provided by patterned lipid lamellae localized to the extracellular spaces between corneocytes.

Mutations in the ABCA12 gene result in congested lipid secretion and impaired barrier function of the stratum corneum (Kelsell et al., 2005).

Multiple studies have established the beneficial effects of niacinamide for improving barrier function of the stratum corneum as measured by TEWL.

The main problem in delivery of drugs across the skin is the barrier function of the stratum corneum (SC), which is located in the outermost layer of the skin [ 16] and consists of corneocytes surrounded by lipid layers.

2, 3 Studies suggest that sensitive skin is the result of impaired barrier function of the stratum corneum, which leads to the exposure of immune system cells and sensitive nerves, resulting in marked cutaneous responses to otherwise harmless stimuli.

Moist occlusion leads to an increased susceptibility for skin friction and the increased skin hydration as well as an increase in skin pH strongly impair the barrier function of the stratum corneum [ 32, 33].

Both the water-holding capacity and barrier function of the xerotic stratum corneum were reported to be restored at least in part following HRT [ 25, 35, 36].

The proteolytic activity of Der p 1 also reduces skin barrier function in nude mice [ 125], disrupting the critical barrier function of the skin mediated by the stratum corneum [ 126] increasing the risk of further allergen sensitisation [ 125].

In the oxazolone induced atopic dermatitis model, the topical activation of PPARα by WY-14643 could normalize the structure of epidermis, significantly improved barrier function of the skin and increased stratum corneum hydration as well as reversed the immunologic abnormalities.

The barrier function of the skin is provided by the stratum corneum (SC), the outermost layer of the skin.

The barrier function of the skin is generally attributed to its upper layer, the stratum corneum.