Sentence examples for barrier function of intestinal from inspiring English sources
MiRNAs play vital roles in the differentiation, architecture, and barrier function of intestinal epithelial cells, and directly and/or indirectly regulate the expression and function of proteins associated with drug absorption in intestinal epithelial cells.
Antimicrobial agents are among the most powerful factors affecting the barrier function of intestinal microbiota [ 18, 19].
111 Butyrate improves the barrier function of intestinal epithelia and has the potential to treat inflammatory bowel disease.
In these Occ −/− mice, the barrier function of intestinal epithelium was normal, but histological abnormalities were found in several tissues (Saitou et al., 2000).
In porcine model, inhibition of ceramide de novo synthesis with mycotoxin fumonisin B1 alters the proliferation and barrier function of intestinal epithelial cells, which in turn leads to induction of inflammation [ 75].
As previously mentioned, the ability of microorganisms to adhere to and alter the barrier function of intestinal epithelia is a key feature that defines their pathogenicity within the intestinal tract reservoir [ 27, 28].
The experiment aimed to test whether DHFZT could increase intestinal blood flow, and protect barrier function of intestine, and then decrease intestinal endotoxaemia in rats with HS.
These proteins are integral to the integrity and barrier function of the intestinal epithelium and such caspase-3 cleavage makes the intestinal barrier vulnerable to potential bacterial paracellular translocation.
Similar mechanisms might also be operating in inflammatory bowel diseases (IBDs) where HIF-1 regulates the barrier function of the intestinal mucosa [37].
Mechanisms that govern the barrier function of the intestinal mucosa are thus of great interest to identify potential targets for novel IBD therapies that can add or synergize with existing therapies.
This weakens immunological resistance and thus diminishes the barrier function of the intestinal mucosa [ 12].
