Sentence examples for barrier function of human from inspiring English sources

The barrier function of human skin models was tested by the application of biotin as tracer molecule.

In summary, we demonstrated that sVCAM-1 directly compromises the barrier function of human brain endothelium by integrin α-4/β-1-mediated induction of intracellular signalling events.

Several in vitro studies have examined the effects of drotrecogin alfa (activated) or plasma-derived human APC on the barrier function of primary human endothelial cells [ 59, 60, 87].

We report here that while chronic exposure to METH disrupts barrier function of primary human brain microvascular endothelial cells (HBMECs) and human umbilical vein endothelial cells (HUVECs), an early pro-survival response is observed following acute exposure by induction of autophagic mechanisms.

The barrier function of the human epidermis is supposed to be governed by lipid composition and organization in the stratum corneum.

In this study, we report that lethal toxin has a profound destructive effect on the barrier function of differentiated human airway epithelium.

This work examines the effect of cyclic AMP (cAMP) on the in vitro barrier function of tubes of human dermal lymphatic microvascular endothelial cells (LECs).

Here, we investigated the expression of sVCAM-1-binding integrins on adult human brain endothelium both under non-inflammatory and inflammatory conditions, and studied whether and how sVCAM-1 affects the barrier function of cultured primary human brain microvascular endothelium.

At these steps, a 4-fold loss of barrier function for pig skin and a 6-fold loss of barrier function for human skin were observed.

In conclusion, the microneedle arrays used in this study are able to overcome the barrier function of the skin in human volunteers, are painless and cause only minimal irritation.

The role of ectodomain shedding for barrier functions of cultured human microvascular endothelial cells (HMVEC-L) was analysed by pharmacological inhibition with GW280264X blocking both ADAM10 and ADAM17.