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The large size molecule is thought to cross the paracellular intestinal pathway only if the intestinal barrier function is compromised.
Furthermore, barrier function is compromised in H. pylori-induced gastritis [ 44], and disruption of the apical junctional complex is associated with gastric cancer [ 45].
Although the epidermis is thicker and the cornified layer is expanded, the number of mature envelopes per unit area of skin is markedly reduced, and barrier function is compromised.
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The data reflect the proportion of these cells compared with epithelial cells, reducing the possibility that a reduction of intestinal dimensions promoted lower functional demand, suggesting that the barrier function was compromised.
Although junctional complexes were evident, junctions were abnormal, and barrier function was compromised in E-cadherin mutant intestine.
The transepidermal water loss (TEWL) was greatly increased when the barrier function was compromised.
Barrier function was compromised, although adherens-mediated cell adhesion appeared intact (Umeda et al., 2006; Umeda et al., 2004).
Thus, mitochondrial function is essential when PP1 function is compromised.
Thus, Mec1p associates with telomeres when their function is compromised.
As discussed above, Treg function is compromised in germfree animals.
Every day another body function was compromised.
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