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Loss of endothelial barrier function can lead to increased endothelial permeability, which results in an anarchical movement of fluid, solutes, and cells outside the vasculature and into the surrounding tissues [ 2], thereby contributing to various diseases such as cancer [ 3], atherosclerosis [ 4], lung injury [ 5], kidney injury [ 6], stroke, and many other diseases [ 7].
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Consequently, dysregulation of miRNA functions can lead to human diseases.
This decreased barrier function can be exploited to achieve direct nose-to-brain drug delivery.
Another advantage of this experimental setup is that barrier function can be monitored in parallel.
6 8 This barrier function can easily be disrupted during mucosal inflammation.
This cultural barrier alone can lead to misunderstandings, even when a language barrier has been overcome.
Since brimonidine crosses the blood brain barrier, it can lead to nervous systemic toxicity [ 124].
This is a classic way to get the guy to break the "touch barrier" and can lead to better things.
Defects in this pump function, as well as in the RPE's outer blood-retinal barrier, can lead to fluid retention and RPE detachment and tears.
Language barriers can lead to social isolation, advocates said, which in turn can lead to mental illness and suicide.
Even small breaks in these barriers can lead to dramatic economic benefits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com