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Remarkably, we found that while Mil embryos had poor epidermal barrier function, as assayed by Texas Red-DextranMW70 permeability, epidermal permeability was significantly reduced with FAK inhibitor.
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Next to this physical barrier, chemical substances take part in the barrier function as well.
Fixed low DO levels reduce the intestinal barrier function as well as absorbing functions.
Glutamine administration may improve gut barrier function as well as lymphocyte function, and this could potentially reduce infectious complications.
For the in vivo data set, analysis of the epithelial barrier defense sub-model predicted that exposure to CS activates mechanisms that lead to decreased epithelial cell barrier function, as well as compensatory mechanisms to restore barrier function.
The FOS induced increase in intestinal permeability reduces intestinal barrier function as reported earlier [ 5].
Disruption of this barrier function as seen during inflammatory processes leads to microvascular hyperpermeability [ 9].
This barrier functions as a sieve allowing transendothelial transport of molecules but inhibiting cellular extravasation.
The intestinal barrier functions as one of the first lines of defense against microbial pathogens [ 55].
Once confluent, endothelial cells were trypsinized, counted, and used in barrier function assays.
Evaluation of barrier function assays was performed using two-way analysis of variance with Holm Sidak post-hoc analysis.
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