Sentence examples for barrier dysfunction due to from inspiring English sources
Other proposed theories are blood brain barrier dysfunction due to small vessel alterations, and consequent chronic diffusion of macromolecules and fluids in the white matter; oxidative stress, endothelial dysfunction and dysfunction of mechanisms of vascular regulation [48].
Another interesting overlap is the angiogenesis pathway shared exclusively between Alz and T1D, especially if interpreted in relation to blood brain barrier dysfunction due to increased vascular permeability induced by hyperglycemia [29].
Thus, secretion of HMGB1 may be an important positive feedback phenomenon that promotes the development of intestinal epithelial barrier dysfunction due to inflammation.
IL-1 receptor KO mice displayed less alveolar barrier dysfunction due to injurious MV (3 hours, VT = 30 ml/kg) when compared with wild-type mice [ 70].
The contribution of blood brain barrier dysfunction due to mitochondrial DNA defects to neurodegeneration remains to be elucidated; however, extravasation of plasma proteins might present an extra burden on neural function.
Reduced perfusion of the gut has also been implicated in post-operative organ dysfunction, due to disruption of the gut endothelial barrier with leakage of endotoxin into the circulation, activating multiple inflammatory pathways [ 21].
Shang, L. et al. beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
Shang, L. et al. Beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.
Interestingly, Vitamin B supplementation restored autophagic flux, alleviated ER stress, and reversed lysosomal dysfunction due to HHCy.
