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In addition, Birukov et al have demonstrated that cultured endothelial cells exposed to pathologic cyclic stretch undergo increased stress fiber formation and are significantly more sensitive to thrombin-induced paracellular gap formation and barrier dysfunction as measured by transmonolayer electrical resistance [13].
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Inhibition of host caspases prevented parasite-induced epithelial barrier dysfunction as well as ZO-1 rearrangement, suggesting the role of caspase-dependent enterocyte apoptosis in host epithelial barrier dysfunction induced by Blastocystis.
A clinical study presented that epithelial apoptoses were upregulated in the colon in Crohn's disease and restored to normal in majority of patients by infliximab treatment [ 33], which correlated with epithelial barrier dysfunction measured as epithelial resistance.
However, all of them had a blood-CSF barrier dysfunction as shown by an elevated QAlb.
Serum KL-6 concentrations are associated with alveolar epithelial barrier dysfunction as they have been shown to correlate with indices of alveolar capillary permeability [ 10].
Unexpectedly, our results point to intestinal barrier dysfunction as a physiological consequence following TBI that is a major factor in subsequent mortality.
VT protected against sepsis-induced endothelial barrier dysfunction, as evidenced by attenuation of vascular leakage and leukocyte transmigration into the peritoneal cavity.
Renal dysfunction, as measured by serum creatinine, corresponds to renal inflammation.
The authors reported the ethnic HDL related dysfunction (as measured by PON1) in nondiabetic women.
Survivors of critical illness have high levels of sleep dysfunction as measured by actigraphy.
This endothelial activation was not translated into endothelial dysfunction, as measured by ED-FMD.
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