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Besides fatty acids and cholesterol, sphingolipids are important skin lipids for barrier acquisition.
The expression of Kruppel-like factor 4 (Klf4), which is highly expressed in the differentiating layers of epidermis and is essential for barrier acquisition [42], is increased in SKO mice.
Keratinocytes of the IFE, HF and SG fulfil different functions to ensure tissue integrity, barrier acquisition and hydration of the skin.
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The availability of biological materials in nature, including dangerous pathogens, and the ability of these materials to replicate, means that there are no technical "chokepoints" where restricting access to materials poses a formidable barrier to acquisition.
This allows us to determine whether insufficient knowledge of the State language is a potential barrier to the acquisition of citizenship.
One of the most important refers to the presence of financial constraints as they constitute a barrier to the acquisition of human capital either when the investment in education is made by parents or by the same potential students (see Solon 2004, among many others).
What is considered normal can be a source of resilience, but also a barrier for the acquisition or implementation of new knowledge.
It is currently unknown if the CRISPR-Cas system also acts as a barrier to the acquisition of antibiotic resistance genes in enterococci.
Alternatively, order sets may serve as a barrier to knowledge acquisition by providers: by listing appropriate patient care interventions, order sets may obviate the need for physicians to seek out and learn appropriate interventions on their own.
Helminth parasites excel at subverting the host's immune regulatory pathways resulting in immunosuppressed hosts harbouring chronic infections 1, 2. This immune suppression forms a major barrier to the acquisition of protective Th2 immunity, both in regard to natural infections and potential vaccination.
Other objectives of this survey were to determine the common uses of remotely sensed data, the common analysis techniques, and whether barriers existed to acquisition and use of geospatial data for forest management.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com