Sentence examples for barrel map from inspiring English sources
Impaired barrel map development due to reduced AC1-dependent phosphorylation of Rab3-interacting molecule 1α (RIM1α), a PKA target in the presynaptic release apparatus [10], impairs neurotransmitter release from thalamocortical afferents in barrelless mice.
These data should be plotted on a normalized barrel map also.
As suggested by the reviewer we performed smoothening of the normalized barrel map (described in Methods section and Figure 6B).
2) When looking at the normalized barrel map, there seemed to be a lower left (presumably aligned to the somatotopic more ventral/posterior position on the face) to upper right gradient of frequency preference.
The idea that input from an orderly organized thalamus alone might not be sufficient to induce a wild type-like cortical barrel map also was found at the level of patterns of expression of developmentally regulated molecules in the reeler brain (Steindler et al. 1990).
With respect to mapping of frequencies in different barrels, see answer to comment 1. Analyses and clarifications conducted with the present data: 1) Did barrel identity in its anterior-posterior position in the barrel map predict the coarseness tuning of cells in that column?
Furthermore, knockdown of SERT expression in serotonin-producing neurons does not impair barrel maps.
This is an essential quantification if they want to answer Reviewer 1's comment since the barrel maps themselves don't look that convincing.
Slices were stained for cytochrome oxidase to reveal the barrel cortex map and then for biocytin with a standard ABC kit (Vectastain), with DAB enhancement to reveal the recorded neurons.
These experiments include 12 maps in which cells were predominantly within the barrel boundaries and three additional maps in which neurons were mostly out of the barrel boundaries (blue P120, red P320, green P600, yellow P1000, white non-preferring neurons and black non-responsive neurons) (Scale bar: 100 µm).
As they barrel through the world's map, they'll inevitably encounter other drivers and synching their game with them is done with the touch of a button.
