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Fig. 1 Barcode representation of a knowledge state.
The ELN provides a QR code or a truncated barcode representation of the associated identifier allowing a flexible labeling.
A SERS nanoparticle label comprises of a noble metal nanoparticle coated with Raman reporter molecules for identification based on their characteristic vibrational Raman spectrum (or barcode representation).
Figure 1D shows the molecular structure of the Raman reporters applied in this study together with their corresponding SERS spectra including a simplified barcode representation (both single "colors" as well as a binary mixture).
The pooling of the samples before PCR resulted in moderately uneven barcode representation (Additional file 2: Figure S2), similar to previous reports [ 26, 27]; this, however, did not adversely affect our genotyping quality.
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Compared with older linear barcodes, 2D barcodes are a machine-readable representation of binary data that possess capabilities of location and tolerance.
Those shRNA vectors that confer resistance to the p53 mediated cell cycle arrest are enriched in the population cultured at 39°C and can be detected as outliers in a MA-plot representation of the barcode microarray experiment (figure 1b).
Firstly, it is not as multiplex as other reduced representation libraries using barcode adapter and pooling procedure.
(A ) Schematic representation of the deep barcoding approach.
Recently, however, next-generation sequencing technologies have been coupled with reduced representation libraries and DNA barcoding to simultaneously identify and genotype a common set of polymorphic loci across a set of samples in a single experiment.
Methods that use reduced representation libraries and multiplex barcoding have been developed to generate genome-wide genotype data from next-generation DNA sequencing that are similar to the data generated from arrays and are suitable for GWA and GS.
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