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If balancing selection has worked to maintain functional binding events during Drosophila evolution, then one would expect to find selective constraint on the nucleotide sequence within binding intervals.
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In other cases, a loss of balancing selection has been observed at MHC [ 15].
Balancing selection has also been used to explain differences between allelic forms that confer different behaviors.
The process is balanced and has worked well since 1993.
On balance, it has worked out well for him.
That balance so far has worked well.
Such weak genetic differentiation indicates balancing selection might have occurred in this region rather than population subdivision.
Thus, balancing selection may have been very intense, leading to strong selection for allelic diversification shortly after the putative bottleneck.
That said, I have worked hard to maintain a balance.
Recent work has revealed that balancing selection mediated either by negative frequency dependent selection or heterozygote advantage can actually decrease rather than maintain MHC polymorphism after a bottleneck [ 64, 65].
Genetic studies have shown that the allelic difference has been maintained by balancing selection [ 81- 83].
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