The new scale is a good balance factor between time and frequency resolution.
The results show the tracking quality/energy consumption trade-off for DIRL, RL, CRL, and Exp3 by varying the balancing factor β between [0.1, 0.9] in 0.1 steps.
A central stratified block randomisation procedure was used to balance prognostic factors between treatment arms and to minimise the predictability of treatment allocation in this open label study.
Despite increasingly frequent implementation of DA methods which aim to balance prognostic factors between treatment arms (Pond et al, 2010), their use remains controversial (Senn, 2000).
It is possible that women's knowledge and understanding of abnormal cervical cytology results and cervical cancer at recruitment might have influenced the psychosocial impact of the management options following colposcopy, but randomisation should have balanced these factors between the arms.
This indicates that in practice, both large interactions between balancing factors and similar numbers of patients in most strata are necessary for a covariate-adjusted analysis to affect type I error rates after balancing within strata.
This demonstrates that, in principle, when randomisation has been balanced within strata, a stratified analysis may be necessary to maintain nominal type I error rates when there are large interactions between balancing factors.
Dynamic allocation (DA) methods (Pocock and Simon, 1975), which balance prognostic factors between treatment groups, often referred to as minimisation (Taves, 1974), are a primarily deterministic, non-random algorithm being implemented with increasing regularity by cancer researchers in clinical trials (Pond et al, 2010).
In the phase II trial design, to balance the prognostic factors between treatment arms, the Pocock-Simon minimization method was used to randomize patients and balance prognostic factors such as ECOG performance status, baseline anemia, nephrectomy, and LDH.
However, our model captures the essential features of transmission, and random allocation of households to the three intervention arms should have balanced all other factors between groups so that the differences in outcomes between intervention groups are due to the effects of the interventions on modes of transmission.
