Exact(5)
Meiotic crossovers (COs) are critical for the balanced segregation of homologous chromosomes at meiosis I. Crossover recombination events between DNA molecules of homologous chromosomes, together with sister chromatid cohesion, establish a physical connection between homologs (chiasmata), which in turn ensures their correct orientation toward oppotiste poles of the meiosis I spindle.
In most eukaryotes this is a prerequisite for genetic recombination and balanced segregation of half-bivalents at anaphase I.
Controlled release of sister chromatid cohesion is essential for balanced segregation of chromosomes in mitosis and meiosis.
One of the most important functions of the centrosome is its role in establishing the bipolar mitotic spindles that orchestrate the precisely balanced segregation of chromosomes.
In addition, the Gifu × L. burttii cross showed a balanced segregation of genotypes, except for the central region of chromosome 2 (Fig. 1D).
Similar(55)
4q terminal deletions often co-occur with terminal duplications of other chromosome as a consequence of imbalanced segregation of a balanced parental translocation.
The use of FISH to confirm deletions and/or duplications detected by microarrays showed that these genomic imbalances resulted from the segregation of a parentally balanced insertion [ 14, 15].
We describe two sibs with a classic WHS phenotype and 4p16.1-p16.3 deletions (~6.5 Mb) due to the segregation of a paternal balanced rearrangement, characterized by karyotyping, FISH, and microarray copy-number analysis.
Retention of sister centromere cohesion during meiosis I and its dissolution at meiosis II is necessary for balanced chromosome segregation and reduction of chromosome number.
Reducing the segregation of the poor is important if India is to attain regionally balanced economic growth.
These included ending "less favourable" treatment of non-Muslims, ceasing segregation of boys and girls, and drawing up a plan to ensure a more "broad and balanced" curriculum.
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