Each of these individual biological functions requires the finely balanced expression of specific genes, a balance regulated through transcriptional and epigenetic gene regulatory networks (Fig. 4, yellow boxes).
Further, inhibition of Errβ or Errγ alter metabolic parameters, whole-body energy balance (e.g. body composition, food intake and neuropeptide expression), while deletion of Errβ reciprocally modulates expression of Errγ (and vice versa) suggesting that balanced expression of Errβ and Errγ is important for control of energy balance and food intake [ 14- 18].
Likely, this is secondary to ameliorated disease states and balanced expression of growth factors and pro-inflammatory factors.
Furthermore, for optimal performance it is essential to have a balanced expression of metabolic pathways.
The result is a beautifully balanced expression of sweet, sour and spicy.
Tissue engineered sheets containing laminin and/or heparan sulfate had a balanced expression of contractile and relaxant motor neurons.
4. Newman ZR, Young ZJ, Ignolia N, Barton GM. (2016) Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.
Effective metabolic engineering of microorganisms relies on balanced expression of both heterologous and endogenous genes to channel metabolic flux towards products of interest while achieving reasonable biomass buildup.
The predominant spices of vanilla and toffee (from the oak) and cinnamon and chestnuts (from the teak) come together in a balanced expression that also includes tropical fruit such as banana and passion fruit but finishes playfully with notes of snickerdoodle.
Thus it is apparent that EBV induces a balanced expression of IRFs during EBV transformation.
To restore the balanced expression of X-linked genes between sexes, gene dosage compensation mechanisms have evolved.
