At the same time, BAD dephosphorylation increases sensitivity of prostate cancer cells to apoptosis.
Values to the left denote small sensitivity – bad response – and values to the right denote high sensitivity -good response.
As the country that taught the cricketing world how to sledge, Australia has not been known for its sensitivity to bad language.
For instance, they may increase managers' sensitivity to bad performance by entrenching them or providing them fewer risk-taking incentives (e.g., decrease the sensitivity of their stock option portfolio to stock volatility, or "vega").
Clive Owen, whose brooding élan would have made him a prime contender, seems out of the running -- which is too bad, since his fluid sensitivity and slender-lipped magnetism supply their own intrigue.
It's the sort of thing that gives sensitivity a bad name and is infinitely inferior to the not dissimilar The Bridges of Madison County, which no doubt its producers sneer at.
Andy Molinsky at Brandeis University and Harvard Business School's Joshua Margolis analyzed why managers find it so hard to perform necessary evils (such as laying off employees and delivering other bad news) with interpersonal sensitivity, which is an important element of process fairness.
In fact, the behaviour of this group of cancers is extremely bad, despite its initial sensitivity to chemotherapy.
Indeed, Gilmore et al. [ 1] showed that transient BAD overexpression enhances the sensitivity of mammary cells to apoptosis, perhaps because the S112 and S136 kinases become limiting.
Using ALL blast mitochondria from 16 samples consisting of primary ALL cells or patient-derived xenografts, we found a statistically significant correlation between mitochondrial sensitivity to BAD BH3 peptide (indicating BCL-2, BCL-XL, or BCL-W dependence) and cell viability determined by half-maximal inhibitory concentration (IC50) values of ABT-199.
