Sentence examples for bacterial vectors from inspiring English sources

Designing bacterial vectors for cancer therapy represents a major challenge.

Edwardsiella tarda is an important facultative intracellular pathogen of both animals and humans, and its attenuated derivates are excellent bacterial vectors for use in recombinant vaccine design.

It presents a strong plea toward rational design of vaccines to address the unsolved vaccine challenges, away from empiric approaches with complicated poorly understood viral or bacterial vectors and away from live attenuated organisms.

In this review, we compare the development of representative live bacterial vectors, and summarize the main characterizations of the various delivery strategies of heterologous antigen in live vector vaccines.

We introduce a novel antiviral approach using bacterial vectors that target avian mucosal epithelial cells and deliver (small interfering RNA) siRNAs against two AIV genes, nucleoprotein (NP) and polymerase acidic protein (PA).

Method signatures present yet another dimension of analyzing pathogens: evidence of potential bacterial genetic engineering may be seen in a genome by checking for traces of the bacterial vectors that may have been used to insert one or more foreign genes and related components into the genome being modified.

Recombinant bacterial vector vaccine is an attractive vaccination strategy to induce the immune response to a carried protective antigen, and the main concern of bacterial vector vaccine is to establish a stable antigen expression system in vector bacteria.

It is an attractive strategy to develop a recombinant bacterial vector vaccine by expressing exogenous protective antigen to induce the immune response, and the main concern is how to enhance the cellular internalization of antigen produced by bacterial vector.

These findings may well have important consequences for the potential utilization of bacterial vector-encoded cytokines in immunoregulation in different disease settings.

Our results suggested that the pUTat-based antigen expression system had great potential with its efficiency and stability in the design of bacterial vector vaccine.

In vitro delivery of an ovalbumin fragment by the bacterial vector into dendritic cells induced the activation of ovalbumin-specific CD8+ T lymphocytes.