The fact that we did not find the guanylate kinase bacterial type in Archaea suggests three possible scenarios: a) a high sequence divergence between these proteins, b) a masking function for some other enzyme, and/or c) a gene loss or gene nonorthologous displacement.
This compares to 38 in S. degradans, 42 in C. japonicus, and 44 in a recently characterized metagenome derived from a community containing over a thousand bacterial types in the hindgut of the termite Nasutitermes sp [22].
First, we analyzed presence/absence of these four bacterial types in all studied patients.
Therefore, the selection of the vector/host system is ideally guided by prior knowledge about the prevalence and distribution of different bacterial types in the sampled habitat.
Examination of bacterial types in subgingival plaque of DT revealed mainly Veillonella, Streptococcus and Capnocytophaga, as observed for low disease COHRA participants.
The addition of phages did not considerably affect the total number of bacteria (Table S2) in any treatment (all cultivations grew to a saturated density of approximately 10 colony-forming units per millilitre; cfu/mL), but rather had an effect on the relative numbers of different bacterial types in a population, often selecting against the multiresistant ones.
The filament is ~10 nm in diameter and is not hollow, resembling more to bacterial type IV pili in this respect [ 10].
This difference in bacterial type may partially explain the difference in the body's reactions to harmful and beneficial bacteria.
Previous studies have shown that PCR amplification of the 16S rRNA gene, a highly conserved region within the bacterial genome, is invaluable in the detection of the bacterial types involved in prosthetic hip joint infections [ 10, 19, 20].
Grouping our patients by the number of different bacterial types found in their periodontal pockets (Table 4), significant changes in oxidative stress levels depended on the number of bacterial types that were found in each group.
