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In 1945 Hershey and Luria demonstrated the existence not only of such bacterial mutants but also of spontaneous phage mutants.
The bacterial mutants exhibiting clear potentiality of enhanced cellulase activity which indicated improved hydrolysis capability were screened.
This chapter describes methods to obtain and analyze bacterial mutants with altered adhesion properties.
Use in prokaryote bioimaging Sensitive and selective staining of bacterial mutants using QD labels was demonstrated by Smith's group.
A dozen of these bacterial mutants also protect the host from age-related progression of tumor growth and amyloid-beta accumulation.
Three mutant SSUs were obtained from spontaneous ValR bacterial mutants and three more were designed on the basis of an alignment of SSU sequences from valine-sensitive and resistant isozymes, or consideration of the molecular model developed here.
Mechanistically, we discovered that five bacterial mutants promote longevity through increased secretion of the polysaccharide colanic acid (CA), which regulates mitochondrial dynamics and unfolded protein response (UPRmt) in the host.
Further, bacterial mutants lacking the pore-forming cytolysin LLO fail to trigger autophagy [23], [24].
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The HAT-RAPD marker revealed the modified polymorphism fragment (615 bp) presenting in the wild type but not in the bacterial mutant.
A bacterial mutant with enhanced PHB production can be distinguished from randomly mixed samples such as random mutagenesis by error-prone PCR in a high-throughput manner using LipidGreen1.
In all simulations, ciprofloxacin-resistant staphylococci were enriched in a concentration-dependent manner, i.e. the higher the AUC24/MIC, the later the onset of mutant selection and the smaller the area under the bacterial mutant curve (AUBCM).
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