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Horizontal gene transfer is a major contributor to bacterial evolution and diversity.
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Understanding the role of recombination and polymorphism in the genetic diversity of an organism, bacterial evolution and emerging pathogens is vital in developing therapeutic or vaccine strategies for a disease [12].
Genetic diversity and genomic rearrangements are a driving force in bacterial evolution and niche adaptation.
Whole genome sequencing techniques have added a new dimension to studies on bacterial adaptation, evolution and diversity in chronic infections.
Because plasmids coexist with chromosomes in bacterial cells, the relationships between plasmids and chromosomes are critical for understanding the evolution and diversity of bacterial genomes.
We quantify homologous recombination in five bacterial pathogens and use these parameter estimates in a multilocus model of bacterial evolution with additive and epistatic effects.
These data represent a major resource for studies of bacterial diversity, evolution and function; however, as the throughput of genome finishing and annotation technologies has not kept pace with sequence determination, the genomes have to be reassembled to be interpreted.
This is because, the researchers say, in bacterial evolution, space, size and geography matter.
We are currently in a race between drug development and bacterial evolution.
Horizontal gene transfer events are observed within other bacterial species and contribute to bacterial evolution [ 12].
Transposition bursts may create more IS copies along with genomic diversity which is essential for bacterial evolution.
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