However, when bacteria were injected to adult stage, TEP was expressed in its proventriculus (Volohonsky et al., 2017).
When injected into muscles, bacteria were restricted to the injected somite for the first hours, but after 24 hours, their fluorescent remnants were observed within motile cells that migrated away from the site of injection (Fig. 1D).
When injected proximal to the sciatic nerve in mice via intramuscular (i.m).
This finding suggests that AP bacteria are somehow "pre-adapted" to invasiveness and, consequently, when injected into mice, they do not undergo much virulence-related changes as they already possess a thicker capsule, lack a functional SpeB, are equipped with surface virulence proteins, and secrete ready-to-use toxins, including the potent DNase, Sda1.
Bifodobacterium, Clostridium, and Salmonella have all been shown to preferentially replicate within solid tumours when injected from a distal site, and all three types of bacteria have been used to transport and amplify genes encoding factors such as prodrug-converting enzymes, toxins, angiogenesis inhibitors, and cytokines.
Thus, Jabba embryos exhibited at least a fourfold decrease in survival when injected with either species of bacteria.
Since DMSO has toxicity to bacteria, DI water was injected to wash out DMSO.
Droplet-bound histones also function in vivo: when injected into Drosophila embryos lacking droplet-bound histones, bacteria grow rapidly.
Female-to-male transsexuals report a similar transformation when injected with testosterone.
We have previously shown that, when injected into the notochord, non-pathogenic Mycobacterium marinum Tes:A mutant bacteria are internalised by notochordal cells as revealed, using TEM, by the presence of the bacteria in endosomes (Alibaud et al., 2011).
Hemocytes contained similar numbers of phagocytic events when injected with either the original or one-fifth of the titers of bacteria (see below), but had too many events to count when the bacteria were five times more concentrated.
