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As it ingests blood, it has to expel water, and it does so through its saliva, accelerating the passage of any hitchhiking Lyme bacteria into the host.
However, there was no evidence shown for direct translocation of PrgJ from the bacteria into the host cell cytoplasm.
The interaction of PrgI with the host membrane stimulates the delivery of effectors from the bacteria into the host cytosol to induce cell death.
Given that the bopA mutant displays a reduced ability to escape the phagosome, it is likely that BopA plays a direct role in disruption of the phagosome membrane, facilitating escape of sequestered bacteria into the host cytosol.
The membrane ruffling engulfs the bacteria into the host cell resulting in their encasement in a vacuole called a Salmonella containing vacuole (SCV), providing these microbes a protective niche for replication [9], [10].
Both the M and C fractions are free of infecting bacteria and any bacterial protein in these fractions must have been transported from the bacteria into the host cell.
Similar(50)
We used this model to investigate the hypothesis that a small subset of the phagocyte population are subverted by internalized bacteria, and permit the release of viable bacteria back into the host, thus providing a population bottleneck, commonly associated with distorted population patterns in ecology.
To model the subset of subverted phagocytes we introduce a population of phagocytes that are termed Infected, F. These are phagocytes that, on initial exposure to a bacterium, are manipulated such that instead of sequestering their contents, they release viable bacteria back into the host.
Infected phagocytes, F, arise from naïve phagocytes with a probability f, they are biologically indistinguishable from Effective phagocytes except that they eventually release their contents as viable bacteria back into the host, with an average burst size of z.
Given biologically identical bacterial strains, the extreme strain ratios at time of death can arise if there is a small probability that a biologically functional phagocyte can be subverted upon infection by S. aureus, such that it is no longer able to sequester its bacterial contents but instead releases viable bacteria back into the host.
Pectinases, as well as cellulases, also assist in penetration of bacteria into the plant host.
More suggestions(15)
bacteria into the reservoir
bacteria into the air
bacteria into the water
bacteria into the gut
bacteria into the food
bacteria into the interior
bacteria into the murine
bacteria into the chicken
bacteria into the bloodstream
bacteria into the mosquito
bacteria into the abdominal
bacteria into the body
bacteria into the environment
bacteria into the plant
bacteria into the pot
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