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Backward rate constant for reaction r.
The forward and backward rate constants for the ion-exchange reaction were determined.
The forward and backward rate functions ( α X and β X for X = CaH, NaF, KDR, KM ) and fixed parameter values are given in Appendix 1.
In this appendix, we state the parameter values and forward and backward rate functions for the Purkinje cell model (Equations 3a-3e), taken from [49].
The calculation of the uncertainty of a backward rate coefficient from the uncertainty of the forward rate coefficient and thermodynamic data is discussed.
The forward rates for the metals are found to be two to three orders-of-magnitude greater than the corresponding backward rate.
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Thus, we can divide the pump operation into three main steps, as is shown in Fig. 5. Initially (A), despite the general trend to move backwards due to the positive trends of the backward rates rr1 and rr6, once r3 is taken, the system might complete easily the cycle in the forward direction, because the forward rates r3, r4, r5 and r6 have a positive trend in the most of the time.
Equilibrium is a state in which no net change in some given property of a physical system is observable; e.g., in a chemical reaction, no change takes place in the concentrations of reactants and products, although the Dutch chemist J.H. van't Hoff had already recognized that this condition results from the equality of the forward and backward rates of a reversible reaction.
To avoid uncertainty of nonlinear regression, an experimental procedure was designed to determine the following four constants in the model: the effectiveness factor, the maximum sorption capacity, and the intrinsic forward and backward rates.
The effect of loss of significant digits in the evaluation of species relations due to substantial cancellation between the forward and backward rates of partial equilibrium reactions was identified and a criterion for minimum accuracy in sampled reaction states for DRG reduction was identified.
With this data, the forward and backward rates of a first order process and its inverse can be estimated, but the multiple constants of more complicated kinetics cannot.
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