(Students might include offering a brief background of the event, choosing essential details, and providing the latest information).
The newspapers, bordered in heavy black, reported daily on the royal family, the historical and ceremonial background of the events and on every aspect of the nation's loss.
The ability to assess a risk of a rare adverse event will depend on the availability of information concerning the background rates of the event in the population of interest.
The background incidence of the events, obtained from EU-ADR, was plotted against the percentage of unilaterally identified signals.
The relationship between the background frequency of the events and the capability of each system to detect signals was also investigated.
In addition, the overall background incidence of the events that were selected was slightly skewed towards more common events and, if our hypothesis holds true, this might have resulted in a bias favouring EHR performance.
The contribution of each system to signal detection appeared to be correlated with the background incidence of the events, being directly proportional to the incidence in EU-ADR and inversely proportional in EudraVigilance.
Spearman's correlation coefficient (R value) was calculated to determine whether there was a correlation between the background incidence of the events and each system's capability to detect signals.
We found a correlation between the background incidence of the events and the contribution of each database to signal detection; the correlation was statistically significant for EudraVigilance but not for EU-ADR, possibly because of the small number of events tested.
The contribution of each database to signal detection appeared to be correlated with the background incidence of the events, being positively although non-significantly correlated in EU-ADR (R = 0.7, P = 0.18) and inversely and significantly correlated in EudraVigilance (R = −1, P < 0.01) (see Fig. 4).
