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Age-matched wild-type C57Bl/6 mice and extensively backcrossed caspase-1 knockout mice or IL-1αβ knockout mice (aged 8 to 14 weeks, weight 25 ± 4 g) with C57Bl/6 background were used in this study.
Arabidopsis thaliana Columbia (Col) wild-type, transgenic plants and mutants in the Col background were used in this study.
The generation of Src KO mice was described previously [45] and these mice along with wild type littermates in C57BL/6 background were used in the experiments.
Three-month old Mas-deficient mice [15] and their wild-type controls, both on a C57Bl/6 background, were used in the experiments.
Since adult C57BL/6 germ cells are more sensitive to radiation-induced death than the SV129 cells, control and mutants of same genetic background were used in experiments.
Eight- to 13-week-old S100A4−/− knockout and wild type mice on an A/Sn genetic background were used in the two experiments.
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Mark Randall's backdrop of two white stripes on a black background was used in both "Abstract Concrete" and "Metal Garden".
The prototrophic CEN.PK strain background was used in all experiments [26].
When LRRK2 T1410A protein in the G2019S background was used in an autophosphorylation assay, the amount of incorporated 33P was reduced compared to G2019S (*p<0.05), indicating the loss of the T1410 phosphoacceptor site (Figure 5C, 5D).
Also the text should state clearly why the Rag -/- mouse background is used in Figure 3 figure supplement 2 and Figure 2B.
These results suggest that a common genetic background was used in the different Aphanomyces resistance breeding programs which selected the different sources of resistance studied.
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