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E1-DN mice in FVB background were generated previously [ 31].
TCPTP-floxed (TCPTPfl/fl) mice on C57Bl/6J background were generated previously [ 33, 34].
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Mice targeted at the Elf5 locus were generated previously in our laboratory [3] and backcrossed for more than 10 generations onto a C57Bl/6 genetic background.
Prodynorphin (Pdyn) gene deletion on C57Bl/6 background were generated as previously described [1].
Shh+/– mice on a C57BL/6J genetic background were generated as previously described, and were obtained from Cyagen Biosciences (Santa Clara, CA, USA).
CD148 loss-of-function transmembrane-knockout (CD148 TM-KO) mice on a C57BL/6 background were generated as previously described.
EC JAM-C-KO (Tie2Cre JAM-C flox/flox ; 129/C57BL/6 background; refs. 17, 27) and EC JAM-C-Tie2Cre JAM-C(C57BL/6 background) were generated as previously detailed.
CCSP-rtTA/Tet-op-K-ras mice (FVB/SV129 mixed background) were generated as previously described (Konstantinidou et al., 2013) and housed in groups of 4 5 with food (either SD or HCD; D12331 from Research Diets) and water available ad libitum in light- and temperature-controlled environments.
Ugt1 mutant mice in the C57BL/6 background have been generated previously (Bortolussi et al., 2012).
CAGGFP-Spry1 transgenic mice on an FVB background were generated as described previously [31].
Mice lacking the gp130 gene in the liver on an atherosclerosis-prone background were generated as described previously [24].
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