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In addition to the mixed-background strain, Col1a1 r/r mice on a C57BL/6J background and 129P1/ReJ background were generated by backcrossing for at least 9 generations.
SOD1G93A mice on a B6 background were generated by crossing B6SJL-TgN SOD1-G93A 1Gur males (Jackson Laboratory) to B6 females for 4 7 generations (N4 N7), and then SOD1G93A mice on an Als2-null background were generated in a similar manner.
The dmpk−/+ heterozygous mice on 129SV background were generated by Reddy et al. [13].
Creb1loxP/loxP mice on a C57Bl/6 genetic background were generated by gene-targeting as described previously [12].
WT, and PRLR KO mice on a pure 129 genetic background were generated by heterozygous crossbreeding [19].
Other double mutants, including ste12ssn8, ste20ssn8, cpk1ssn8, and SSN8 overexpression in the cwc1 mutant background, were generated by crossing the strains with appropriate genotypes.
Similar(31)
Image background is generated by material that is stained but not part of a protein spot.
A second background was generated by a 3rd order Markov model (RSAT package [ 10]).
Cngb3−/− mouse line (on C57BL/6N background) was generated by targeting deletion (Deltagen Inc., San Mateo, CA) as described previously (31).
The Δ laeA mutant strain in the ATCC11414 background was generated by homologous replacement of laeA in the ATCC11414 Δ kusA derivative (Chiang et al. 2011).
Akt1-/ and Akt2-/ mice of C57BL/6 genetic background were generated and provided by Dr Morris Birnbaum Howard Hughess Medical Institute, University of Pennsylvania, Philadelphia, PA, USA) [ 5, 6].
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