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COMP-deficient mice in the 129/Sv background were backcrossed for 10 generations against B10.Q mice, which are susceptible to chronic CIA.
Male SOD1 G93Adl mice on a hybrid C57BL/6J-SJL/J background were backcrossed for at least three generations onto C3H/HeH, FVB/J and BALB/cAnNCrl, and for at least eight generations onto C57BL/6J.
Male SOD1 G93Adl mice on a C57BL/6J × SJL/J (C57BL/6J-SJL/J) hybrid background were backcrossed for at least three generations into four different inbred lines: C57BL/6J ('backcrossedossed to generation N8), BALB/cAnNCrl, C3H/HeH and FVB/J.
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Since penetrance of the ApcMin mutation is affected by genetic background, the K- rastmΔ4A allele on a F1(129/Ola × C57BL/6) background was backcrossed for a further 8 generations on to the susceptible C57BL/6 inbred background.
Heterozygous ROCK2 mice in C57BL/6 background were backcrossed to FVB background for more than eight generations.
These mice, originally on a FVB/N background, were backcrossed onto a C57Bl6/J background for more than 10 generations.
A1-KO mice, originally generated in a mixed genetic background C57/Sv129, were backcrossed for more than 10 generations in C57Bl/6J.
Progenies used in aging assays and metabolite profiling experiments were prepared by mating wild-type animals of Canton-S background, which were backcrossed for seven generations.
While generated on the FVB background, they were backcrossed for five generations to SJL/J before being shipped to Northwestern University, where they were then crossed with Thy1.1 congenic SJL/J mice (backcrossed more than 12 generations to SJL/J).
MMC transgenic mice (previously named MMC-1), which originated on the C3H.Q background as described previously [ 10], were backcrossed for eight generations onto the B10.Q background.
HVEM-/ and LIGHT-/ mice were backcrossed for 9 generations to C57BL/6 background.
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