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Socioeconomic background was derived using the Townsend Index.
The estimated proportion of each PCT population from a BME background was derived from the Office for National Statistics (ONS) Population Estimates by Ethnic Group PEEGG) for 2009.
There were some faint TUNEL-positive cells detected in the solvent-treated tumors, indicating that this background was derived either from a solvent effect or from spontaneous tumor cell apoptosis.
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Myd88−/−, TLR2−/−, Tlr4−/−, mice (129SvJ×C57Bl/6 background) were derived as previously described [2] and backcrossed for six generations with C57Bl/6 mice.
IL-2-deficient mice [41] on a C57BL/6 background were derived at the Institute, and DEREG mice [28] were generously provided by Tim Sparwasser.
NIL3, NIL12 and NIL3 12 possessing the deepwater response QTL on chromosomes 3, 12 and 3/12 in the T65 genetic background were derived previously (Hattori et al. 2009).
CCR2−/− mice on a C57BL/6J background were derived as described previously (23) and backcrossed to C57BL/6J mice from the Jackson Laboratory (Bar Harbor, ME, USA) for 6 generations.
Bscl2-deficient mice (Bscl2−/−) in C57BL/6 J background were derived from a colony at Georgia Regents University, which was originally derived from a colony at Baylor College of Medicine, with backcrosses to C57BL/6 J background for five generations.
Female Chrna7 knockout mice (originally described by Orr-Urtreger et al. [ 17] on a C57BL/6 J background were derived from heterozygous breeding of animals obtained from Jacksons Laboratories (Bar Habor, ME, USA).
A large number of D. subobscura isochromosomal lines for the O chromosome in an otherwise homogeneous genetic background were derived from an outbred stock collected at Puerto Montt (Chile; 41° 28' S) in November 1999 as previously indicated [ 38].
Male and female mice homozygous null for the Apoe gene on a 71% C57BL/6J, 29% 129/SvJ background, were derived from a closed outbred colony housed in the Animal Unit of the University of Bristol.
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