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In typical microarray experiments, quantified spot intensities are corrected with a local background value based on the intensities of pixels just outside the spot area.
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Therefore, if a relatively high background value based solely on the reference station had been used for comparative analyses, the significance of Fe and Cu at the stations near the platform would have been underestimated.
We set a lower detection limit (background signal) for the normalized p24 values based on the highest results that we found for a donor that was homozygous for the 32 base pair deletion in CCR5.
The background could be illustrated by the difference between modeled values (based on local sources) and measured values (local sources and regional background).
The peak finding method applied here does not use input control data for background subtraction nor does it rank peaks by P-values based on a statistical model.
If the attacker has background knowledge of the data (BKD), they can reveal plaintext values based on distinguishable ciphertexts as we show in the following example.
Probes were assigned a detection P-value, based on their signal overlap with the background distribution.
Significance for over (or under) -representation was assessed using P-values based on Fisher's Exact test when compared to background motif frequency.
The left curve with mean 0.04 and standard deviation 0.02 denotes IGpe values obtained based on background distributions, and the right curve with mean 0.36 and standard deviation 0.06 denotes IGpe values based on conditional distributions.
cp-value based on ANOVA.
In this algorithm, raw intensity values are background corrected based on a model using sequence information followed by quantile normalization [ 60, 61].
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CEO of Professional Science Editing for Scientists @ prosciediting.com