Sentence examples for background selection and locus-specific from inspiring English sources

The distribution of heterozygosity at SSR loci can be shaped by selective sweeps, background selection and locus-specific differences in mutation rates.

With a broader selection of loci, locus-specific LINE-1 methylation could become a tool for tumor detection.

There is possibility that RAD loci's nucleotide diversity is influenced by background selection and selective sweeps on linked loci [ 37, 38].

Therefore, background selection is unlikely to be the major factor affecting the disparate ratios of variant to invariant repeats across chromosomes: mutation rate variation, divergent levels of different repeat types across chromosomes and locus-specific effects, such as selection, are more likely.

It should be noted that the FST-based tests of selection are prone to false positives because of sensitivity to demographic history [ 51], heterozygosity among loci in mutation rate [ 52] and locus-specific phenomena not related to selection [ 48].

Loci experiencing the strongest Y linkage exhibit inflated levels of sequence diversity, which is contrary to expectations from background selection and selective sweeps.

Finally, the influence of background selection and other selective forces such as hitchhiking on the genomic reduction of substitution rate in conifers is mostly unknown, although selective sweeps following bottlenecks have been reported for several loci [ 22, 23, 90].

If the strength of background selection and the recombination rates are similar across species, background selection will have similar effects in different lineages, reducing both diversity and divergence, and the overall effect will be similar to a reduction of mutation rate at the neutral locus.

Placing one of the PCR primers within a highly repeated element might cause weak amplification, high background and difficulty in locus-specific amplification [ 10, 27, 52].

However, these effects affect all loci in the genome indiscriminately, while natural selection is locus-specific [3], [31].

Selection, which causes locus-specific bottlenecks, is one of the factors that increases LD between selected alleles at linked loci.