Sentence examples for background regimen from inspiring English sources
Patients received 600 mg of darunavir and 100 mg of ritonavir twice daily plus an investigator-selected optimized background regimen.
Versus Efavirenz 600mg q.d. in Combination With a Background Regimen Containing 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Antiretroviral-naive HIV-1 Infected Subjects.
In addition to a high concordance with in vitro measured fold change, which was the primary aim of model design, the models per drug show good predictivity of therapy response for regimens including that drug, even in the absence of other clinically relevant factors such as background regimen.
In areas where second line drugs are available, adding thioridazine to an optimized background regimen may improve therapy outcome, which, to date, has been disappointing [17], [18].
The optimal second-line background regimen to combine with TMC207 and the duration of treatment with such regimen are not known.
The additional efficacy of thioridazine within an optimized background regimen should be subject of future mouse model studies and thereafter randomized controlled trials.
Background: Regimens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals have not been widely adopted given concerns regarding efficacy, adherence and drug resistance.
Few patients were treatment-naïve, and trials increasingly used designs with provisions for add-on to established "background" regimens.
After a ten-day period, the background regimens were optimized to include active drugs, while continuing dolutegravir.
The clinical success may still possibly be achieved by maximizing the number of active drugs in the background regimens and improving the adherence of patients.
The Protocol 005 study was a phase II, double-blind clinical trial, which investigated the safety and efficacy of raltegravir in combination with optimized background regimens (OBT) in HIV-infected patients with multidrug-resistant virus.
