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Synonymous sites usually evolve neutrally and can provide insights on the background rate of sequence evolution [ 59, 60], thus we used the K s values of protein-coding genes to estimate neutral substitution rates in sticklebacks.
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Each of these approaches requires significant manual examination of the results to extract true-positives from a high background rate of spurious predictions and to precisely describe the sequence changes caused by mutations that lead to structural variation.
TFBS prediction was done on 1001 bp regions, to extend sequences sufficiently far into the flanks to present the background rate of TFBS prediction.
The background rate of primary ovarian insufficiency was therefore higher than the rate after HPV vaccination.
We include a background rate of disease which may represent sporadic cases, or the effect of genetic background.
Step 1: Background rates ○ The overall background rate of cardiovascular hospital admissions for Ireland is 638.9 per 100,000.
Background shows background rates of other labrid clades under the two-rate model.
Moreover, O157 H7 has an apparently normal long-term rate of sequence change14.
Background rate as function of basal area.
Yet, gene expression data allow for selection of sequences in which binding sites should occur at a background rate in the context of the particular biological condition.
We present a non-stationary epidemic-type aftershock sequence (ETAS) model in which the usual assumption of stationary background rate is relaxed.
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