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On the other hand, if a large proportion of the general population has asymptomatic gallstones, our risk estimates regarding gallstones are likely to be underestimated as the background population was used for comparison.
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D3 ES cell-derived populations were used to determine background fluorescence at each time point.
After determination of motif (word-matching in the nucleotide string) or module (word-matching separated by flexible gaps) abundance, enrichment or depletion in the experimental dataset compared to the randomized background population is calculated using a standard Z-score.
The background population was set to 6,359 (the number of genes annotated in GO) and P values were corrected for multiple testing using Bonferroni.
The prevalence in the background population was 2.2% (Table 1).
Data about the background population were uploaded from Statistics Denmark.
Characteristics of the study population and the background population are shown in Table 1.
Comparison between study population and background population is shown in Table 2.
Local background subtraction was used to facilitate background correction.
No activity in the background was used.
A Shirley-type background was used.
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