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It is thus likely that the differences in the genetic background of these populations mean that other genes or different variants are underlying the disease.
This difference might be due to different genetic background of these populations and/or to a different intensity of transmission in the studied areas or to environmental factors.
In practice, however, the true ancestral populations may not be found, and even if they are found, the genetic background of these populations may have drifted from that of the original ancestral populations.
These regions are of particular interest to understand the natural and human selective pressures to which these subspecies were exposed to and how the genetic background of these populations evolved in response to environmental challenges and human manipulation.
Levesque et al. [ 18] also reported differences in NOS2 promoter polymorphisms and malaria severity between populations of Tanzania (East Africa), Gabon (Central Africa) and Gambia (West Africa), suggesting differences in the genetic background of these populations.
These regions are of particular interest to understand the natural and human selective pressures to which these subspecies were exposed and how the genetic background of these populations evolved in response to environmental challenges and human manipulation.
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Moreover, the results may depend on the genetic background of the population, the type of cancer, the type of thrombosis, and the chemotherapeutic treatment.
In contrast non-mandatory data are expected to vary among different sleep centers due to sociocultural background of the population, available equipment or limited resources (e.g. CSF hypocretin levels).
In principle, it is possible to infer population structure from associations between marker loci and from associations of markers with the trait, even when no information about the demographic background of the population is available.
LD is population specific and is expected to change with recombination, genetic background of the population and effective population size.
This may reflect local experience and the nature, ethnic and religious background of the population of North West London.
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