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The different genetic background of our population could also account for the lack of replication.
It is difficult to compare our results with those of other studies because of the differences in the biological samples used to measurement exposure, and the genetic background of our population; however, we found a negative association between prenatal PFOS levels and birth weight, especially in females, consistent with some previous reports (Apelberg et al. 2007; Maisonet et al. 2012).
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In summary, despite differences between the study designs and differences in the genetic background of our populations our results are consistent with the similar studies reported by Simmons, Ubol and Kruif [27], [28].
Only 4% of our MPs come from an ethnic minority background – compared with 14% of our population.
Although previous studies commonly reported association between Khat chewing and alcohol consumption [ 10, 28, 29], our finding revealed a different picture, which is largely attributable to the predominantly Moslem religious background of our study population where alcohol consumption is prohibited.
However we did not find any differential expression of these genes that might account for the reported content in AsA among the RILs, indicating that their expression do not determine the final AsA content in tomato fruit in the genetic background of our RILs population.
Racial stratification was not performed as around 90% of our population is of Caucasian background.
The large sample size and broad genetic background of our tested populations allowed us not only to confirm previously reported QTL, but also to identify novel QTL and candidate genes.
These conflicting findings might be a result of differences in the genetic and ethnic backgrounds of our study population.
The self-administered questionnaire was translated into Bangladeshi, Myanmar, English, Hindi, Tamil, and Telugu, reflecting the linguistic backgrounds of our study population, with accuracy of translation verified through back-translation to English.
Firstly, we described the background characteristics of our study population.
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